The Hulk possesses the potential for limitless physical strength depending directly on his emotional state, particularly his anger. This has been reflected in the repeated comment, "The madder Hulk gets, the stronger Hulk gets." The cosmically-powerful entity known as the Beyonder once analyzed the Hulk's physiology, and claimed that the Hulk's potential strength had "no finite element inside."[66] Hulk's strength has been depicted as sometimes limited by Banner's subconscious influence; when Jean Grey psionically "shut Banner off", Hulk became strong enough to overpower and destroy the physical form of the villain Onslaught. Writer Greg Pak described the Worldbreaker Hulk shown during World War Hulk as having a level of physical power where "Hulk was stronger than any mortal—and most immortals—who ever walked the Earth." His strength allows him to leap into lower Earth orbit or across continents, and he has displayed superhuman speed.

His durability, regeneration, and endurance also increase in proportion to his temper.Hulk is resistant to injury or damage, though the degree to which varies between interpretations, but he has withstood the equivalent of solar temperatures, nuclear explosions, and planet-shattering impacts.] Despite his remarkable resiliency, continuous barrages of high-caliber gunfire can hinder his movement to some degree while he can be temporarily subdued with intense attacks with chemical weapons such as anesthetic gases, although any interruption of such dosages will allow him to quickly recover. He has been shown to have both regenerative and adaptive healing abilities, including growing tissues to allow him to breathe underwater,[83] surviving unprotected in space for extended periods,[84] and when injured, healing from most wounds within seconds, including, on one occasion, the complete destruction of most of his body mass.[85][86] As an effect, he has an extremely prolonged lifespan.

He also possesses less commonly described powers, including abilities allowing him to "home in" to his place of origin in New Mexico; resist psychic control,or unwilling transformation; grow stronger from radiation or dark magic; punch his way between separate temporal or spatial dimensions; and to see and interact with astral forms. Some of these abilities were in later years explained as being related; his ability to home in on the New Mexico bomb site was due to his latent ability to sense astral forms and ghosts, since the bomb site was also the place where the Maestro's skeleton was and Maestro's spirit was calling out to him in order to absorb his radiation.[86] The Hulk is also able to generate omnidirectional bursts of kinetic energy that completely destroy the planet he is standing on.