Corporal mortification is regularly practiced in Opus Dei. It is perhaps one of the most startling aspects of Opus Dei life for people outside the group. Many of the practices of corporal mortification were at one time more regularly practiced within the Church; however, due to modern psychology and thinking, the practices which inflict pain are sometimes considered to be counterproductive to one's spiritual development, as they can easily lead to pride and an unhealthy attitude toward one's body.

Some acts of corporal mortification may be helpful in checking the desires of the flesh, such as fasting. However, in Opus Dei, especially for the numerary (celibate) members, all of the practices mentioned below are mandatory if one wishes to live the "Spirit of Opus Dei" fully. The "Spirit of Opus Dei" is the standard of living, as outlined by the Opus Dei directors, for which all truly dedicated Opus Dei members strive. Under the umbrella of the "Spirit of Opus Dei" hide many of the abuses in Opus Dei. The subtle control to conform to the norm is typical in groups which practice mind control; members are "guilted" into conforming, feeling that they must in order to follow "God's will" as it is outlined by the controlling group.

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