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Goto-Kakizaki
#14
Lineman
MA
7
ST
3
AG
3
AV
7
R
0
B
0
P
0
F
0
G
8
Cp
0
In
0
Cs
3
Td
0
Mvp
1
GPP
11
XPP
0
SPP
11
Injuries
n
Skills
Block
Albino originating at Tohoku University, Sendai, Japan in 1975.
The Goto-Kakizaki rat is an excellent model of Non-Insulin Dependent Diabetes Mellitus (NIDDM), type II diabetes. It exhibits similar metabolic, hormonal and vascular disorders to the human diabetes disease.Unlike many other rodent models of Type II diabetes, the GK rat is non-obese.
Characteristics of the Goto-Kakizaki rat include fasting hyperglycemia, impaired secretion of insulin in response to glucose both in vivo and in isolated pancreatic cells, hepatic and peripheral insulin resistance. Late complications such as retinopathy, microangiopathy, neuropathy and nephropathy have been described in literature
The Goto-Kakizaki rat is an excellent model of Non-Insulin Dependent Diabetes Mellitus (NIDDM), type II diabetes. It exhibits similar metabolic, hormonal and vascular disorders to the human diabetes disease.Unlike many other rodent models of Type II diabetes, the GK rat is non-obese.
Characteristics of the Goto-Kakizaki rat include fasting hyperglycemia, impaired secretion of insulin in response to glucose both in vivo and in isolated pancreatic cells, hepatic and peripheral insulin resistance. Late complications such as retinopathy, microangiopathy, neuropathy and nephropathy have been described in literature
Match performances
Date
Opponent
Comp
TD
Int
Cas
Mvp
Spp
2003-11-04
-
-
-
-
1
5
2003-12-18
-
-
-
1
-
2
2004-01-02
-
-
-
1
-
2
2004-02-29
-
-
-
1
-
2