You only get one blitz per turn, so use it wisely. When planning your turn (yes, you should be planning most of what you'll do) you need to work out what you want your blitz to do. There are numerous different things to do with a blitz, depending on the situation.


Offence Blitz Moves:
- Punch a hole in the opponent's line to move through
- Blitz to roll yuor cage forward


Defensive Blitz moves:
- Blitz the opponent's ball carrier
- Blitz to try to put tackle zones on the opponent's ball carrier
- Blitz your opponent's catcher if it's likely the ball will be thrown to them


Blitz moves to do any time:
- Blitzing a player into the crowd (remember to move away again, otherwise you might also get pushed into the crowd)
- Blitzing to set up a block (possibly into the crowd)
- Blitzing to try to knock down a key opposing player or to tie up another of their players
- Blitzing to free up one of your key players (such as a catcher, the ball carrier, or a player with a sick skill)

(if anyone has any more suggestions for this list, please PM me)

Important note:
I personally feel that blitzing with big guys is generally not a great idea. All big guys have some restriction which means that there is a chance they won't take their action this turn. In the case of a blitz, this uses up your only blitz for the turn. Also, not many big guys have block, and none of them can use a team reroll, so they tend to fall over a lot, which ends your turn.
On the upside however, they're usually your strongest player, and so will get 2 or even 3 dice to choose from, making them quite effective blitzers even without assists from your other players.