Patrick Henry (May 29, 1736 – June 6, 1799; Hanover County, Virginia) was a prominent figure in the American Revolution, known and remembered primarily for his "Give me liberty or give me death" speech. Along with Samuel Adams and Thomas Paine, he was one of the most influential (and radical) advocates of the American Revolution and republicanism, especially in his denunciations of corruption in government officials and his defense of historic rights.

Trained as an attorney, and noted for his heated oratorical skills, this Virginian first made a name for himself in a case dubbed the "Parson's Cause" (1763), which was an argument on whether the price of tobacco paid to clergy for their services should be set by the colonial government or by the Crown. Henry technically lost the case, but damages were set at such a nominally low level that the result was widely perceived to be a victory for the independence movement. Perhaps in part because of his success in this venture, Henry was elected to the House of Burgesses (the legislative body of the Virginia colony) in 1765. That same year, he proposed the Virginia Stamp Act Resolutions. The freshman representative waited for an opportunity where the mostly conservative members of the House were away (only 24% was considered sufficient for a quorum). In this atmosphere, he succeeded, through much debate and persuasion, in getting his proposal passed. It was possibly the most anti-British (many called it "treasonous") American political action to that point, and some credit the Resolutions with being one of the main catalysts of the Revolution. The proposals were based on principles that were well established British rights, such as the right to be taxed by one's own representatives. They went further, however, to assert that the colonial assemblies had the exclusive right to impose taxes on the colonies and could not assign that right. The imputation of treason is due to his inflammatory words, "Caesar had his Brutus; Charles the First his Cromwell; and George the Third—" [Cries of "Treason! Treason!"] "George the Third may profit by their example. If this be treason, make the most of it."

According to biographer Richard Beeman, the legend of this speech grew more dramatic over the years. Henry probably did not say the famous last line of the above quote, i.e. "If this be treason, make the most of it." The only account of the speech written down at the time by an eyewitness (which came to light many years later) records that Henry actually apologized after being accused of uttering treasonable words, assuring the House that he was still loyal to the king. Nevertheless, Henry's passionate, radical speech caused quite a stir at the time, even if we cannot be certain of his exact words.

Henry is perhaps best known for the speech he made in the House of Burgesses on March 23, 1775, urging legislature to take military action against the encroaching British military force. The House was deeply divided, but was very much leaning toward not committing troops. As Henry stood in Saint John's Church in Richmond, Virginia, he ended his speech with his most famous words:

Is life so dear, or peace so sweet, as to be purchased at the price of chains and slavery? Forbid it, Almighty God! I know not what course others may take; but as for me, give me liberty or give me death!

The crowd jumped up and shouted "To Arms! To Arms!". This speech is credited by some with single-handedly delivering the Virginia troops to the Revolutionary War. Problematically, the text of this speech did not appear in print until 1817, in the biography Life and Character of Patrick Henry by William Wirt. Although Wirt assembled his book from recollections by persons close to the events, some historians have since speculated that the speech, or at least the form with which we are familiar, was essentially written by Wirt decades after the fact.

Early in the Revolutionary War, Henry led militia against Royal Governor Lord Dunmore in defense of some disputed gunpowder, an event known as the Gunpowder Incident. During the war, he served as the first post-colonial Governor of Virginia, from 1776-79, an office he held again from 1784-86.

After the Revolution, Henry was an outspoken critic of the United States Constitution and urged against its adoption, arguing it gave the federal government too much power. As a leading Antifederalist, he was instrumental in forcing the adoption of the Bill of Rights to amend the new Constitution. He became a strong opponent of James Madison. By the late 1790s he was a prominent Federalist in support of Washington and Adams. The irony is that most of his followers became Republicans who supported Jefferson's party. President George Washington offered him the post of Secretary of State in 1795, which he declined. In 1798 President John Adams nominated him special emissary to France, which he had to decline because of failing health. He strongly supported John Marshall and at the urging of Washington stood for the House of Delegates in 1799 as a staunch Federalist. He especially denounced the Virginia and Kentucky Resolutions, which had been secretly written by Jefferson and Madison, and approved by the legislatures of those two states. He warned that civil war was threatened because Virginia, "had quitted the sphere in which she had been placed by the Constitution, and, in daring to pronounce upon the validity of federal laws, had gone out of her jurisdiction in a manner not warranted by any authority, and in the highest degree alarming to every considerate man; that such opposition, on the part of Virginia, to the acts of the general government, must beget their enforcement by military power; that this would probably produce civil war, civil war foreign alliances, and that foreign alliances must necessarily end in subjugation to the powers called in." He was elected to the House of Delegates, but died three months prior to taking his seat. [Tyler, 413-20] He died at Red Hill Plantation, Virginia, in 1799 at the age of 63.