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Rain Ocampo (played by Michelle Rodriguez) is one of only two female members of One's commando team. She was the group's most skilled marksman, and had at least one close friend in J.D. Salinas. In the novelization, Rain's last name is given as Melendez and it is revealed that she joined Umbrella because being female was an obstacle to joining any other SWAT team; this was similar to a later role of actress Rodriguez in the movie S.W.A.T.
In Resident Evil, Rain was able to get the train into the Hive working, and held Matt Addison prisoner. Shortly after, Rain, J.D., and Matt Addison were attacked by a horde of zombies while waiting for their teammates. Rain was bitten on the hand, thus becoming infected with the T-Virus, and she sustained more bites over the course of the film, speeding up the rate of infection. When trapped in a sealed room, the Red Queen informed the survivors that Rain would have to be killed, because of the infection, in order to let the rest of them go. Alice refused and although Rain was injected with the anti-virus, she transformed into a zombie aboard the escape train. Presumably the infection had simply progressed too far at that point to be cured, and thus Matt was forced to shoot her in the head.