In Resident Evil: Extinction, where the world has succumbed to the T-Virus, Alice has separated from the group. She stays on the move to avoid capture by the Umbrella corporation after she learned Umbrella could track her through satellites. She left the group to protect them, using the satellites trajectories to stay off the grid. On her travels she finds a journal detailing the possibility of Alaska as sanctuary. However, the Umbrella corporation is utilizing the White Queen, a more advanced artificial intelligence computer that is able to find Alice. Early in the film, she uses her telekinesis to save Claire Redfield's Convoy; the convoy in which L.J. and Carlos have since joined. However, Alice is noticed by an Umbrella satellite, and Isaacs is then made aware of her location. The leaders of the convoy, decide to make the trip to Alaska, but first refuel in Las Vegas. Isaacs goes after Alice, defying orders from Umbrella Chairman Albert Wesker.