Djedefre (also known as Djedefra and Radjedef) was an ancient Egyptian king (pharaoh) of 4th dynasty during the Old Kingdom. He is well known under his Hellenized name form Ratoises (by Manetho). Djedefre was the son and immediate throne successor of Khufu, the builder of the Great Pyramid of Giza; his mother is not known for sure. He was the king who introduced the royal title Sa-Rê (meaning “Son of Ra”) and the first to connect his cartouche name with the sun god Ra.

He married his (half-) sister Hetepheres II. He also had another wife, Khentetka with whom he had (at least) three sons, Setka, Baka and Hernet, and one daughter, Neferhetepes. These children are attested to by statuary fragments found in the ruined mortuary temple adjoining the pyramid. Various fragmentary statues of Khentetka were found in this ruler's mortuary temple at Abu Rawash. Abu Rawash actually sits at an elevation higher than the rest of Giza, making it the highest, albeit not the tallest, pyramid. Some historians claim that the "pyramid" at Abu Rawash isn't even a pyramid at all; instead, it may be a "sun temple." Archaeologist Vassil Dobrev has claimed that it may not even be Djedefre's. Excavations by the French team under Michel Valloggia have recently added another potential daughter, Hetepheres, as well as a son, Nikaudjedefre, to this list.

Statue of Setka inscribed with his name and titles, Musée du Louvre.
Djedefre married his brother Kawab's widow, Hetepheres II, who was sister to both of them, and perhaps married a third brother of theirs, Khafre, after Djedefre's death.